33x12.50R15 is 0.00" taller than 33x10.50R15, a ±0.00% change in diameter, inside the 3% range most shops treat as a safe swap.
Ground clearance changes by 0.00" (half the diameter change), and the tire needs 0.00" more room above it.
33x12.50R15 is 2.00" wider. On the same wheel offset about half of that, 1.00", moves toward the suspension and half toward the fender.
Both fit a 15" wheel; the sidewall is 0.00" taller on 33x12.50R15.
Details: 33x10.50R15 in inches · 33x12.50R15 in inches · change sizes in the calculator